Publications

McHugh T, Welburn JPI. Dynein at kinetochores: making the connection. (2017). JCB. 216(4): 855-857.

Gigant E., StefanuttiM, LabandK, Gluszek-KustuszA, EdwardsF, MatonG,LacroixB, CanmanJC., WelburnJPI , DumontJ. Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7MCAK prevents oocyte aneuploidy. (2017) Development. 

Legal T., Zou J., Sochaj A., Rappsilber J., Welburn JPI. Molecular architecture of the Dam1 complex-microtubule interaction. (2016). Open Biology. DOI: 10.1098.

Kajtez J., Solomatina A., Novak M., Vukušić K., Polak B., Rüdiger J., Milas A., Šumanovac Šestak I., Risteski P., Cojoc G., Roscioli E., Welburn J., Cimini D., Glunčić M., Pavin N., Tolić IM. Overlap microtubules link sister k-fibers and balance the forces on bioriented kinetochores. Nat Communications. 7 (2016)  link.

Cell Scientist to Watch- Julie Welburn (2015). 128(4465-4466). Journal of Cell Science.

 

Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway.
Anna A. Ye, Jovana Deretic, Christopher M. Hoel, Albert W. Hinman, Daniela Cimini, Julie P. Welburn, Thomas J. Maresca. Current Biology. (2015)

 

The C-terminal regiostructure talapatran of the motor protein MCAK controls its activity and structure through a major conformational switch.

Talapatra S., Harker B., Welburn JPI. Elife. (2015)

 

 

Analysis of microtubule dynamic regulators highlights length-dependent anisotropic scaling of spindle shape.

Young S., Besson S., Welburn JPI. Biology Open. (2014). 3:1217-1223. 

 

The molecular basis for kinesin functional specificity during mitosis. 

Welburn J.P. Cytoskeleton (2013).
[PubMed]

Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition

Syred HM,  Welburn J.P., Rappsilber J, Ohkura H. Mol Cell Proteomics (2013). 

[PubMed]

The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle

Welburn J.P.I. & Cheeseman I.M. Mol Biol Cell (2012).  
[PubMed]

Aurora B phosphorylates spatially distinct targets 

to differentially regulate the kinetochore-microtubule interface.

Welburn J.P.I., Vleugel M., Liu D., Yates III J.R., Lampson M.A., Fukagawa T., Cheeseman I.M. Mol Cell (2010). 38: 383-92. 

[PubMed]

The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility.

Welburn J.P.I., Grishchuk E.L., Backer C.B., Wilson-Kubalek, E.M., Yates III J.R., and Cheeseman I.M. Dev Cell (2009). 16: 374-385. 

[PubMed]

Towards a Molecular Structure of the Eukaryotic Kinetochore.

Welburn J.P.I. and Cheeseman I. M. Dev. Cell (2008). 15: 645-655. 

[PubMed]

 

 

 

The Constitutive Centromere Associated Network makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore.

Hori T., Amano M., Suzuki A., Backer C. B., Welburn J.P.I., Dong Y., McEwen B. F., Shang W-H., Suzuki E., Okawa K., Cheeseman I. M. and Fukagawa T. Cell (2008). 135:1039-52. 

[PubMed]

Architecture and microtubule-driven assembly of the Dam1 kinetochore ring complex.

Wang H.-W., Ramey V., Westermann S., Leschziner A., Welburn J.P.I., Nakajima Y., Drubin D., Barnes G. and Nogales E. Nat Struct Mol Biol. (2007). 14: 721-6. 
[PubMed]

How tyrosine 15 phosphorylation inhibits the activity of CDK2/cyclin A.

Welburn J.P.I., Tucker J., Johnson T., Morgan M., Noble M. and Endicott J. J Biol Chem. (2007). 282: 3173-81. 
[PubMed]

mol cellMolecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3.

*Macdonald N., *Welburn J.P.I., Noble M., Endicott J., Nguyen, Yaffe M., Clynes D., Moggs J., Orphanides G., Thomson S., Edmunds J. and Mahadevan L.C. Molecular Cell (2005). 20: 199-211. * equal contribution to the paper. 

[PubMed]

Cell cycle inhibition: a targeted approach.

Welburn J.P.I., Endicott J. Seminars in Cell and Developmental Biology (2005). 16, 369-381. 
[PubMed]

Methods for preparation of proteins and protein complexes that regulate the eukaryotic cell cycle for structural studies.

Welburn J.P.I., Endicott J. Methods Mol Biol. (2004). 296:219-36. 
[PubMed]